The researchers reveal SARS-CoV-2 tissue and virus-specific innate immune responses of human nasal-mucosal and lung tissues.
“The study sheds light on the role of the nasal-mucosa in active viral transmission and immune defence, suggesting a window of opportunity for early interventions, in contrast to the restricted innate immune response in early SARS-CoV-2 infected lung tissues which could underlie the unique uncontrolled late phase lung damage of advanced COVID-19.”
To the paper
To Prof. Wolf lab