In the article, the researchers identify and characterize two cell populations that contribute to bone loss during chronic inflammatory diseases.
“Our findings suggest a central role of inflammatory osteoclast precursors in (iOCPs) bone loss initiation. iOCPs can serve as potential biomarkers for inflammatory bone loss (IBL) detection, and possibly as new therapeutic targets to combat IBL in a wide range of inflammatory conditions.”
Figure 2b: Representative 3D modeling from femoral microCT scans of control (cont.) and inflamed (inf.) mice.
