In the three articles, published back-to-back, the researchers specify the need to study chronic inflammation related immune suppression, and show how robust chronic inflammation can be performed in-vivo. They later elaborate on different methodologies to evaluate the related immune suppression using various in-vivo and ex-vivo immunological assays.
Figure 4: Immunofluorescence images showing the distribution of myeloid-derived suppressor cells (MDSCs) stained with the pan-MDSC marker Gr-1 (green) in the spleens of control (A) and inflamed (B) mice. Evident is the morphology of T (red) and B (orange) zones within the spleen and MDSCs surrounding these structures.
To the Prof. Baniyash lab
To the 1st article
To the 2nd article
To the 3rd article