In the article, the researchers report the synthesis of 3 novel CBG derivatives, which carry anti-inflammatory and analgesic properties.
We believe that HUM-223, HUM-233 and HUM-234 have the potential for development as novel drug candidates for the treatment of inflammatory conditions, and in the case of HUM-234, potentially for obesity where there is a huge unmet need.
Figure 6: Anti-obesity evaluation of HUM-234 (25 mg/kg) in comparison to CBG (15 mg/kg), HFD (high fat diet) and STD (standard food diet).
