Congratulations to Prof. Ofer Mandelboim and MD-PhD student Yoav Charpak-Amikam for their new article published in Nature Communications!
In the article, they found that Natural Killer (NK) cells play a role in the immune response against Candida albicans, a common fungal pathogen and a prevalent cause of deadly bloodstream infections. They also found that the fungal cells can inhibit NK cells and that by blocking the NK-fungi inhibitory interaction, using immunotherapy with a […]
Congratulations to Prof. Ofer Mandelboim and PhD student Rebecca Kotzur for publishing a new paper in the Journal PLOS ONE!
In the paper they show that NK-92 cells, the most “NK-like” cell line currently available, can grow and thrive in RPMI medium supplemented with IL-2, instead of a costly and complicated specific medium used up until now. Presently a therapeutic platform in clinical trials and an important research tool, this discovery can aid scientists in […]
We warmly welcome Prof. Nir Friedman and his lab as the newest members of the Lautenberg Center!
Prof. Friedman uses innovative computational biology techniques to study chromatin and gene regulation. We also like to congratulate Prof. Friedman and his team for their recent publication in Nucleic Acids Research! In their study, the researchers showed how cells regulate the balance between mRNA production and degradation. Figure 1a:cDTA-seq and genome-wide transcript half-life estimation. To […]
Congatulations to Prof. Michal Lotem and Ph.D student Rony Shreberk-Hassidim for their new article published in Immunologic Research!
In the article, the researchers aimed to explore the role of Immune Checkpoint Receptors (ICR), which modulate the immune response in T cell malignancies such as cutaneous T cell lymphoma. They show a regulatory role of ICR, mainly PD-1 and its ligand PD-L1, on cutaneous T cell malignancy. To the paper To Prof. Lotem lab
Congratulations to Prof. Dana Wolf and Ph.D student Or Alfi for their article, published in Viruses!
In the article, the researchers investigated the mucosal susceptibility and immune response to Omicron as compared to Delta and earlier SARS-CoV-2 variants of concern (VOCs). They found that the replication of the Omicron variant in lung tissues is highly restricted when compared to other VOC, whereas it remained relatively unchanged in nasal tissues. Omicron also induced […]
The 1st semester of the 2022-2023 academic year began a few weeks ago! Congratulations and good luck to all the Lautenberg Center students and teachers!
𝐀𝐟𝐭𝐞𝐫 𝐬𝐮𝐦𝐦𝐞𝐫 𝐯𝐚𝐜𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐭𝐡𝐞 𝐡𝐨𝐥𝐢𝐝𝐚𝐲𝐬, 𝐰𝐞’𝐝 𝐥𝐢𝐤𝐞 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐟𝐞𝐰 𝐠𝐫𝐞𝐚𝐭 𝐞𝐯𝐞𝐧𝐭𝐬: 𝟏. 𝐓𝐡𝐞 𝟐𝟎𝟐𝟐 𝐝𝐞𝐩𝐚𝐫𝐭𝐦𝐞𝐧𝐭𝐚𝐥 𝐑𝐞𝐭𝐫𝐞𝐚𝐭 included the awarding of the James Sivartsen Prize – click here for more info and photo gallery https://lautenbergcenter.org/the-lautenberg-center/annual-retreats/ 𝟐. 𝐓𝐡𝐞 𝐈𝐌𝐑𝐈𝐂 𝐜𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞 𝐚𝐧𝐝 𝐓𝐡𝐞 𝐑𝐚𝐛𝐛𝐢 𝐒𝐡𝐚𝐢 𝐒𝐡𝐚𝐤𝐧𝐚𝐢 𝐀𝐰𝐚𝐫𝐝 𝐨𝐟 𝟐𝟎𝟐𝟐: https://lautenbergcenter.org/the-lautenberg-center/shai-shaknai-award/ 3. We were very honored to have had […]
Congratulations to Prof. Dana Wolf for receiving a Ministry of Science and Technology of Israel research grant!
Prof. Wolf developed a unique method to study viral infection mechanisms of respiratory tracts, which enables the study and further development of new potential anti-viral therapies. To the Wolf lab
Congratulations to Prof. Michal Baniyash and her team for their articles published in Current Protocols in Immunology!
In the three articles, published back-to-back, the researchers specify the need to study chronic inflammation related immune suppression, and show how robust chronic inflammation can be performed in-vivo. They later elaborate on different methodologies to evaluate the related immune suppression using various in-vivo and ex-vivo immunological assays. Figure 4: Immunofluorescence images showing the distribution of myeloid-derived suppressor cells (MDSCs) stained with […]
Congratulations to Prof. Rami Aqeilan and his former Ph.D. student Dr. Hussam Husanie for their article published in Cell Death and Disease!
In the article, the researchers found that the protein WWOX may play a key role in the development and progression of pancreatic cancer. When WWOX was deleted in mice, it led to the formation of precancerous lesions and pancreatic cancer. Overexpression of WWOX in human pancreatic cancer cells reduced their aggressiveness in both lab and […]
Congratulations to Professor Nir Friedman for receiving the prestigious Landau Prize from the Mifal HaPais Council for Culture and the Arts!
This award recognizes Professor Friedman’s exceptional contributions to the field of computational biology, particularly in the development of machine-learning techniques for analyzing human genomes in the medical field. His pioneering work, which has allowed for highly sensitive measurements of DNA fragments in blood samples and has been widely cited in scientific research, has helped pave […]