The Lautenberg Center is proud of having four of our very own faculty included within the Faculty of Medicine Rector’s ‘Excellence in Teaching’ list for 2020-2021 academic year! Congratulations!
Prof. Michael Berger Prof. Michal Baniyash Prof. Rami Aqeilan Prof. Eli Pikarsky
Congratulations to Ruth Galily for her new article published in Molecules!
In the article, the researchers report the synthesis of 3 novel CBG derivatives, which carry anti-inflammatory and analgesic properties. We believe that HUM-223, HUM-233 and HUM-234 have the potential for development as novel drug candidates for the treatment of inflammatory conditions, and in the case of HUM-234, potentially for obesity where there is a huge […]
Congratulations to Prof Michael Berger and his team on their new article published in Journal of Biological Chemistry (JBC)
In the article, the researchers study changes in T cells water mass during cell activation and growth. Our work provides a method to analyze cell water content, as well as insights into the ways cells regulate their water mass. Figure 2: T cell growth is associated with a gradual decrease in wet to total volume ratio […]
Congratulations to Prof. Michal Baniyash and Dr. Yaron Meirow for their new paper published in Nature Bone Research!
In the article, the researchers identify and characterize two cell populations that contribute to bone loss during chronic inflammatory diseases. “Our findings suggest a central role of inflammatory osteoclast precursors in (iOCPs) bone loss initiation. iOCPs can serve as potential biomarkers for inflammatory bone loss (IBL) detection, and possibly as new therapeutic targets to combat […]
The LRC/CL mourns the passing of Joyce Powell from Los Angeles, California.
Joyce was among the pioneers who funded Concern Foundation back in the 1960s. She was an ardent supporter of cancer research at the LRC for more than five decades. She was a unique character that inspired the community of the Concern Foundation and the many young researchers supported by Concern grants. Senior LRC Faculty and […]
Congratulations to Prof. Dana Wolf and PhD. Student Olesya Vorontsov for their article published in The Journal of Clinical Investigation !
In the article, the researchers aimed to identify prognostic biomarkers of CMV-related fetal brain injury and identified two amniotic fluid proteins that could be employed in the clinical setting to profoundly improve the prognostic assessment of CMV-infected fetuses. Figure 4. Amniotic fluid chemerin (A) and Gal-3BP (B) levels in fetuses with severe cCMV (SCC), sensorineural hearing […]
Congratulations to Prof. Ofer Mandelboim and Dr. Pini Tsukerman as their company, Nectin Therapeutics Ltd., received FDA approval to initiate clinical trials
Congratulations to Prof. Ofer Mandelboim and Dr. Pini Tsukerman as their company, Nectin Therapeutics Ltd., received FDA approval to initiate clinical trials using their monoclonal antibody, NTX1088. The clinical trials will assess the immune checkpoint modulation profile and safety of NTX1088. To Nectin web
Congratulations to Prof. Ofer Mandelboim and MD-PhD student Yoav Charpak-Amikam for their new article published in Nature Communications!
In the article, they found that Natural Killer (NK) cells play a role in the immune response against Candida albicans, a common fungal pathogen and a prevalent cause of deadly bloodstream infections. They also found that the fungal cells can inhibit NK cells and that by blocking the NK-fungi inhibitory interaction, using immunotherapy with a […]
Congratulations to Prof. Ofer Mandelboim and PhD student Rebecca Kotzur for publishing a new paper in the Journal PLOS ONE!
In the paper they show that NK-92 cells, the most “NK-like” cell line currently available, can grow and thrive in RPMI medium supplemented with IL-2, instead of a costly and complicated specific medium used up until now. Presently a therapeutic platform in clinical trials and an important research tool, this discovery can aid scientists in […]
We warmly welcome Prof. Nir Friedman and his lab as the newest members of the Lautenberg Center!
Prof. Friedman uses innovative computational biology techniques to study chromatin and gene regulation. We also like to congratulate Prof. Friedman and his team for their recent publication in Nucleic Acids Research! In their study, the researchers showed how cells regulate the balance between mRNA production and degradation. Figure 1a:cDTA-seq and genome-wide transcript half-life estimation. To […]