Congratulations to Prof. Ben-Neriah and his team on their newest and exciting findings published in Nature!
In the article, Prof. Ben-Neriah and his team show that mutant p53 has an oncogenic effect in the distal gut but a tumor-suppressive effect in the proximal gut, and these opposing properties are determined by the gut microbiome. To the paper Watch a Youtube video review of the project by Eleanor Sheekey
Congratulations to Dr. Oren Parnas and his team on their newest publication in Nature Communications.
Their fascinating and important research applies single cell RNA-seq to uncover important players in the early development of pancreatic cancer, a disease with shockingly low survival rates. For more about their valuable discoveries click here. To the paper
Congratulations to Michael Berger for your well-deserved promotion of associated professorship!
Prof. Michael Berger
Prestigious research grant from the European Research Council for Dr. Yotam Drier
Dr. Yotam Drier was awarded 1.5 million euros from the European Research Council (ERC). The ERC grant will support the Drier lab’s quest to understand epigenetic and topological alterations in cancer and their intratumoral heterogeneity. These efforts include both uncovering fundamental mechanisms that regulate epigenetics and topology, as well as translating these findings to improve treatment of specific […]
Prof. Ofer Mandelboim published a new paper in Nature Communications!
Dr. Einat Seidel led this exiting work into a new role for a human cytomegalovirus-derived signal peptide which is slowly cleaved, enabling it to function in immune evasion! Click here to read more about this important and impressive discovery. To the Mandelbiom lab
Congratulations to Prof. Dana G. Wolf and PhD Student Or Alfi for the recent publication of their novel study in the Journal of Virology !
The researchers reveal SARS-CoV-2 tissue and virus-specific innate immune responses of human nasal-mucosal and lung tissues. “The study sheds light on the role of the nasal-mucosa in active viral transmission and immune defence, suggesting a window of opportunity for early interventions, in contrast to the restricted innate immune response in early SARS-CoV-2 infected lung tissues […]
Congratulations to Prof. Michal Lotem and Dr. Emma Hajaj!
Prof. Lotem and Dr. Hajaj have discovered that two splice variants of the SLAMF6 receptor are found on human T Cells. While one form has a known antagonist role, the other form acts as an agonist that contributes to the anti-tumor response of T Cells. They show that promoting mRNA splicing, resulting in an elevated […]
Will the mRNA vaccine technology be used to treat autoimmune diseases?
“I realized that I had already done this more than 10 years ago, performing research that showed the potential for mRNA vaccines to combat autoimmune diseases and cancers.” Says Prof. David Naor. To the paper To Prof. Naor lab
Passing through the new tunnel connecting the Botnar Building to Magid, don’t miss this:
Beautiful picture by PhD Student Or Reuven of Prof. Michal Baniyash’s lab, showing immune cells localized together in response to a developing tumor. To Prof. Baniyash lab
Congratulations to Prof. Berger and Dr. Saragovi for their article published in e-Life!
In their research, Prof. Berger and Dr. Saragovi used a unique mouse model to examine T-Cell antiviral responses in mice which were kept under low oxygen conditions. Using molecular, pharmacological, and genetic methods they showed that T-Cell failure to respond under hypoxia stems from mitochondrial biogenesis arrest. They then demonstrated that hypoxia-arrested T cells in-vivo […]