Will the mRNA vaccine technology be used to treat autoimmune diseases?
“I realized that I had already done this more than 10 years ago, performing research that showed the potential for mRNA vaccines to combat autoimmune diseases and cancers.” Says Prof. David Naor. To the paper To Prof. Naor lab
Passing through the new tunnel connecting the Botnar Building to Magid, don’t miss this:
Beautiful picture by PhD Student Or Reuven of Prof. Michal Baniyash’s lab, showing immune cells localized together in response to a developing tumor. To Prof. Baniyash lab
Congratulations to Prof. Berger and Dr. Saragovi for their article published in e-Life!
In their research, Prof. Berger and Dr. Saragovi used a unique mouse model to examine T-Cell antiviral responses in mice which were kept under low oxygen conditions. Using molecular, pharmacological, and genetic methods they showed that T-Cell failure to respond under hypoxia stems from mitochondrial biogenesis arrest. They then demonstrated that hypoxia-arrested T cells in-vivo […]
Congratulations to Prof. Michal Baniyash and Prof. Rami Aqeilan, for receiving the 2021 Israel Science Foundation Grant!
Read more To Prof. Aqeilan lab To Prof. Baniyash lab
Congratulations to Prof. Rami Aqeilan and MD-PhD student Daniel Steinberg for their newly published article in EMBO Molecular Medicine!
This study opens a new avenue for studying Developmental and Epileptic Encephalopathies in a human context, providing insight into a hitherto rare topic. Moreover, it serves as a platform to study possible therapeutic intervention, and although further study is required before clinical translation, the data serves as a proof-of-concept for the use of genetic therapy […]
It is with great sadness that the Lautenberg Research Center announces the passing of Ben Perlmutter z”l
Ben and his wife, Ruth, were long time substantial benefactors of the LRC. They played an instrumental role for many years and in many projects, such as in fundraising for the construction of the new facilities at Hadassah Ein Karem. Their partnership directly helped the Lautenberg Research Center improve and expand our research capabilities. Prior […]
New Review published on Trends in Cell Biology
A fascinating and intriguing review on the putative homeostatic role of cancer mutations is published by Prof. Yinon Ben Neriah, Prof. Eli Pikarsky, and PhD student Avanthika Venkatachalam. In this review the authors discuss the potential constructive role of driver mutations in maintenance of tissue homeostasis, and whether they are linked to augmented stem cell […]
Together with eminent virology colleagues from Italy and Germany, Prof. Dana Wolf organized the European Seminar in Virology.
The exciting program, with leading state-of-the art speakers and students from all over Europe, put an emphasis on SARS-CoV-2. Discussions included neutralizing antibody responses to SARS-CoV-2 variants, vaccines, other viral agents, antiviral vaccine vectors, and vaccine development against SARS-CoV-2. In addition to SARS-CoV-2, other viral infections were also well-represented, including intrinsic restriction factors to HIV and […]
Congratulations to Emeritus Professor David Naor and his team for for their article published in the Journal of Autoimmunity!
They weren’t done there; further congratulations are due to Prof. Naor and his team for receiving a prestigious Ines Mandl Research Foundation grant! Read more To the paper To Prof. Naor lab
Congratulations to Prof. Rami Aqeilan and his post-doctoral researcher Dr. Sri Repudi for their new paper published in EMBO Molecular Medicine on the preclinical assessment of WWOX gene therapy as a possible treatment for WOREE syndrome.
“In this study, we showed that a single ICV injection of AAV9-Syn1-WWOX in Wwox-null neonates rescues the phenotypes associated with WWOX deficiency including growth retardation, hypoglycemia, hypomyelination, seizures and premature lethality.” says Prof. Aqeilan. “Additionally, treated mice were fertile and exhibited normal behaviour” he added. This proof-of-concept preclinical assessment provides hope for WOREE and SCAR12 […]